This book review highlights Dr. Marty Makary’s exploration of how groupthink, tradition, and flawed assumptions have led medicine astray despite its many advances. Reflecting on the COVID-19 pandemic and broader medical history, the review praises Makary’s call for humility, open inquiry, and a renewed commitment to truth. Rather than discrediting medicine, the book challenges physicians to confront dogma and pursue evidence-based reform with integrity and courage.